Growth Factors in Skincare: What Is EGF and Why Is Everyone Talking About It?
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Growth Factors are naturally occurring proteins that help cells communicate. In skincare, Epidermal Growth Factor (EGF) is used as a cosmetic ingredient in formulations designed to support the appearance of healthy-looking skin.
As advanced skincare continues to evolve, EGF has become one of the most talked-about ingredients in premium formulations. This guide explains what Growth Factors are, why EGF has gained attention, which ingredients work well alongside it, and how Nēaē Skin incorporates it into CentellaBIO™.
What Are Growth Factors?
Growth Factors are proteins found naturally in the human body that act as signalling molecules between cells. Different Growth Factors perform different functions depending on where they occur in the body.
In cosmetic skincare, EGF (Epidermal Growth Factor) is one of the best-known Growth Factor ingredients. It is produced using modern biotechnology to create a cosmetic-grade ingredient suitable for use in topical skincare products.
Unlike ingredients such as Hyaluronic Acid, which focuses on hydration, or Niacinamide, which supports the skin barrier and overall complexion, EGF belongs to a different category of cosmetic ingredient. This makes it a popular choice in advanced multi-active formulations.
Why Is EGF Becoming So Popular?
The skincare industry has gradually shifted from products built around a single hero ingredient to formulations that combine several complementary actives.
EGF fits naturally into this approach because it is often paired with ingredients that support hydration, barrier care, and overall skin conditioning. Rather than relying on one ingredient alone, modern formulations are designed so multiple ingredients work together as part of a complete skincare routine.
This philosophy is at the heart of many next-generation skincare products, including those developed by Nēaē Skin.
Which Ingredients Work Well with EGF?
EGF is commonly combined with other cosmetic ingredients to create balanced, multi-active formulations. Some of the most popular pairings include:
- PDRN (Polydeoxyribonucleotide) — a DNA-derived cosmetic ingredient increasingly featured in premium skincare
- Centella Asiatica — a botanical ingredient widely used in barrier-focused skincare
- Ceramide Complex — helps support the skin’s natural moisture barrier
- Rosehip Oil — a nourishing botanical oil rich in essential fatty acids
- Grape Exosomes — a plant-derived ingredient featured in select next-generation formulations
- Niacinamide — a versatile ingredient that supports hydration, skin tone, and barrier care
- Hyaluronic Acid — one of the most recognised ingredients for long-lasting hydration
Together, these ingredients represent the modern approach to skincare: carefully balanced formulations designed to complement one another rather than relying on a single active. Explore the full Face Serums & Skincare collection to see how Nēaē Skin combines them.
How Nēaē Skin Uses EGF
At Nēaē Skin, EGF is one of the key ingredients in CentellaBIO™, part of The Next Gen Longevity Collection™.
CentellaBIO™ combines EGF with Grape Exosomes, PDRN, Centella Asiatica, Ceramide Complex, and Rosehip Oil in a single evening face cream designed to simplify your skincare routine while bringing together multiple advanced cosmetic ingredients.
It can be used on its own as your evening moisturiser or as the final step in The Nēaē Skin Routine Cycle.
Where CentellaBIO™ Fits in Your Routine
For your evening routine:
- Cleanse with the Hyaluronic Acid Cleanser
- Prepare the skin with the Hyaluronic Acid Toner
- Apply your preferred Drip System™ Serum — Collagen Drip 35%, Salmon DNA Drip 30%, or Glowing Drip 28%
- Finish with CentellaBIO™ to complete your routine
CentellaBIO™ is formulated as a complete face cream, so no additional moisturiser is needed.
Frequently Asked Questions
What does EGF stand for?
EGF stands for Epidermal Growth Factor, a naturally occurring protein used as a cosmetic ingredient in advanced skincare formulations.
Can EGF be used with other skincare ingredients?
Yes. EGF is commonly formulated alongside ingredients such as Hyaluronic Acid, Niacinamide, Ceramides, Centella Asiatica, and PDRN in multi-active skincare products.
Is EGF suitable for daily use?
Usage depends on the individual product. Always follow the directions provided with your skincare product.
Can EGF be used with retinol?
Many people include both ingredients in their evening skincare routine. If introducing either ingredient for the first time, add them gradually and observe how your skin responds.
Are Growth Factors the same as peptides?
No. Growth Factors and peptides are different types of cosmetic ingredients, although they are often used together within the same formulation.
Discover EGF with Nēaē Skin
If you’re looking to introduce Growth Factors into your skincare routine, CentellaBIO™ combines EGF with PDRN, Grape Exosomes, Centella Asiatica, Ceramide Complex, and Rosehip Oil in one complete evening face cream.